I don't see why not, I used to play a Fender Bandmaster Reverb head thru my Mesa 2-12 rectifier cab which had Vintage 30's in it and it sounded graet for Blues. I would think the CL90's would be even better since they are neutral sounding speakers which will let more of your amps natural tones to shine .
it's really is depend on the type of sound you want to get. Blues tone usually great with a more inefficient speakers. i have a 6l6 amp that i run through a 1X12 thiele loaded with EV so i would have to use a drive pedal to get light break up from my amp.