I do. I use Mighty Mite C4 chrome covered actives and I also run a maxon OD808. I am a metal player though. I dont know what kind of music your into. But in the metal scene emg 81s boosted by a TS type pedal into the dirty channel of a high gain amplifier with the gain rolled back is the recipe for metal these days. Listen to any song by killswitch engage and that is what your hearing.
BOGUS! The reason i bought active p/u's in the first place was to drive the effects. They work fine with any kind of effect, and they're dead quiet on stage, and in the signal chain. EMG SA's in a strat back in the 80's, when everything was way overprocessed was the ticket then, and quite frankly it still works well today.
I had a set of emg kerry kings with the boost switch back a while ago. They ripped they were allot of fun. Even though they were supposed to be metal pickups you could pull off allot of different types of music with them
ive always used a overdrive for a lead boost, all my guitars have emg's @ 18v
they all sound fine it mostly depends on your amp.
right now i use a way huge green rhino, its an amazing tubescremer clone with more knobs, sounds great!
before that i had a ts9, wylde od, coffin blood drive and a sd-1
my first od pedal was a DoD but o forget what it was called lol
i usually set everything to noon and tweak to taste, i remember the everything at 1:00 setting on a tubescremer usually sounds pretty good