1. Red Snapper (when I owned one) -->E: Nice tones, gave the E a bit more thickness, and a tone very similar to Mayer's "Good Love Is On The Way" from the TRY! album. That one use wasn't worth holding on to the Snapper.
2. OCD-->E: With the OCD's gain up about 2:00 and the Eternities gain at about 12:00, gives really nice, cutting lead tones and really chunky rhythm tones. This really kills in a band situation
3. Tejas-->E: Set the level knob of the tejas at about 3:00, drive at 12:00 (not much hair) and the drive on the E at about 2:00 and it gives a really great, thick lead tone. almost D*mble esque. This is what I use most, and it really yields some great tone.
4. E-->Fat Boost....Thickens up and gives a volume boost...great for leads in a live setting.