Quack is a compromise. Lowering pickups helps but other factors are heavily involved including saddle material strings trem vs hardtail action or height of strings even pick material and where over the pickups do you play. Add to that the right amp to achieve that too. Its a tough chase and if you just focus on positions 2 and 4 the rest will suffer by being too thin sounding to do much else imo. Once you get the pickups as close to the tones that they are capable of a good eq pedal can do the rest. And you can use it for every gtr you own to tweak out and fine tune those tones too.