I purchased an '82 Tokai '62 Strat reissue. I had to decide whether to refret the neck or replace it. The pickups had gray fiber bobbins marked "E", which were OEM at that time for this model (I read made by DiMarzio). They sounded nice but anemic. I swapped the neck. The result in sound was dramatic, as though the same old pickups sprung to life. Only then did I replace the saddles and harness, which also improved the sound from the pickups. I'm of the belief that everything affects everything. Shoot, I even heard a difference when I changed the intonation saddle screws to stainless ones, and not for the better, imo.