OK, sound is subjective, almost any amp will sound great as long as it is properly built, it doesn't matter if it is handwired or not, or if it is PCB or some oher construction technique. General types of contruction techniques: Eyelet/turret circuit board. Resistors, capacitors and wires are soldered on an eyelet/turret board and wire leads are soldered to and from the board. This type of construction is easy to trouble shoot and repair. It is more labor intense as there are extra solder joints and wire to assemble the amp. All of the extra solder joints and added wire are potential points of failure. And lead dress has to be spot on. Eyelet/turret circuit board/PTP. This is similar to the above, but some of the resistors and capacitors terminate directly to its origin or destination. This reduces the number of solder joints and can ease some lead dress issues. Terminal strip. There are some amps that use the terminal strips in place of eyelets or turrets. The big advantage (and disadvantage) is quality mechanical connections. Terminal strip/PTP. This is the best of both, resistors and capacitors are supported by the terminal strips. Fewer wire leads are needed and fewer solder joints are present. True PTP This type of construction is only feasible on simple, well layed out circuits. the leads of the resistor/capacitor are soldered directly to the origin or destination, no added wire is used. This type is more reliable because of fewer solder joints. But can be more labor intense to troubleshoot and repair. Every solder joint in an amp is a potential point of failure. The type of mechanical connection used can minimize or induce the chances of failure.