I had a Mesa 22+ that was not noisy other than some low level hiss that is common with these amps. If the noise is loud the amp needs servicing.
I didn't really like mine until I swapped the speaker with an Eminence Private Jack and removed the tone shift capacitor which is automatically switched in on the lead mode. Both of these mods reduced mids.
I'd take one over a Blues Jr, but they are very different amps.