Hi In this little pedal board I'm using currently on a theatre show I've got (in order serially): A Boss NS2 (noise suppressor) A Maxon OD808 (overdrive) An Ernie Ball 25k volume pedal A TC Flashback (delay) and A TC Hall Of Fame (reverb) The NS2 and the OD808 both have buffers that can not be defeated. But the buffers in the two TC pedals can both be turned off for true bypass operation. Would it be better to keep both of the TC pedals in true bypass mode or should I turn on the buffer in the last effect in the chain? Also... How bad is it, sonically speaking, to have two buffers in a row at the beginning of the chain? I originally bought the OD808 [vs the OD-9 (which is true bypass)] because I learned that the buffer in the OD808 had a very good reputation and I had planned on having it as the 1st pedal in the chain. But some of the cues in this show require me to have my vol pedal cranked between playing sections and the little bit of noise from my pickups was getting a bit annoying so I had to add the NS2. My research tells me that the NS2's buffer is pretty good as well. But I'm not wild about having two buffers in adjacent pedals right at the beginning of the effects chain.