Yes, and, in fact, I absolutely recommend sticking to TS cables, because the MIC-IN has phantom on it that cannot be turned off, and it's way too easy to end up with an XLR in the wrong combo jack. I do use XLR cables, but ONLY into the LINE-IN combo jack (no phantom there). I can see why some folks would prefer the YP for the wood cabinet, but, in my case, I needed the coax configuration to be able to tolerate the horn at close range. Try both, see what works for you. Are you looking for a guitar monitor (i.e., backline) or a full band monitor (i.e., wedge)? I managed to convince my local L&M to bring in a Tech 21 Power Engine Deuce Deluxe (ignoring the "special-order-only" status these things seem to have), and, as a backline solution, it is amazing. It sounds huge, has amazing presence, and, for my money, it eats the Power Cab for lunch. But it's not a wedge, and if you need floor monitoring, I'd still recommend the NX10c (or the YP-10).