I know this topic has been debated many times on TGP before but this last weekend I heard without a doubt that speaker cables (even a mere 20" of it) make a noticeable difference in sound/tone. I have a Tweed Deluxe based amp that I wanted to make period correct/as accurate looking to a real 50's 5E3 as possible. So I ordered a replica cab and waited 9 months for the cabinet to arrive. The cabinet is made with real Hide Glue! Then I proceed to scour the Internet in search of a speaker cable/plug just like the original ones. I found a source and got a the black speaker plug with cloth wire in 18AWG. When I got it, I was very happy that the plug looks exactly the part. So this weekend I take out the current speaker cable with is a Evidence Audio Siren II with push on connectors. I crimped on the same push on connectors on the replica NOS speaker cable to try it out. I turn the amp back on and immediately notice there's less volume, less bass and less cabinet rattle. I try it out a big longer to see if I like the tone change and after some playing decide it's thinner/less mids and not as good sounding. I swap back to the Evidence Audio cable and my tone goes back to normal. Both cables where about the same length, 20". Some people might say that it's all in my head and I'm hearing with my eyes, but it was the whole cabinet rattle thing that was immediately noticeable. I had rushed to put the chassis back in a few days ago and hadn't taken the time to adjust the chassis up against the back panel to get rid of the rattle. So when the new cable went it, the reduction in bass and volume was immediately signaled by the significantly less cab rattle. I wanted the NOS vintage cable to work so bad so I could have a perfect replica amp but unfortunately the change in sound is too noticeable for me to want to keep the cable in there. So there you have it, I'm now a firm believer that even speaker cables make a difference.