Well, I can only go by my previous experience. I'm sure you have read that players try to dial in any amp they use for their choice of specific tones.
On some amps, such as Vox and related amps, the chime and glassiness will come naturally, and of course single coils enhance that experience.
If I want that aspect of an amp when I play, I have found that I would have to switch to an amp that offers that tone as part of the inherent sound the amp will put out from how it's wired.
I have tried getting a glassy sound from some amps I used to use, but I have not had the success I desired in achieving that tone. Also, I use humbuckers for the tones I need, as I have the lightest gauge strings I can find, 7-32, so I have to find ways to artificially boost the fatness of my tone as a result.
If I wanted more glassy tones, I would opt for Fenders and Vox. Some amps might put out these sounds, but they might tend to sound phony, or artificial, compared to other amps.
Everything influences everything else.the pickup,pickup height,caps,pedals,amp preamps,gain stages,eq,pi,ot,output valves,cathode or fixed biased,speakers,cabinet,room,net voltage,humidity,temperature.and, if it,s not that then.....you.
Before all the other "changes" noted here. I recommend 2 simple things. first. Change the angle of your speaker cab in relationship to the room and your ear. Second. Try using a different pick. Buy 30 different types if you must I promise you they will all sound differently. It's a lot cheaper to buy a pick than it is cables, speakers,cabs, amps.
If you can't find a pleasing tone with those 2 changes. It mostly likely is not the equipment but a greater expectation of your abilities than is factual.