For months last year I was playing a 335 plugged directly into my Super Reverb then sometime during the fall, after putting a pair of SROs in my 4x12, I switched to playing through my Rivera Knucklehead Reverb.
During the last month I've been playing my HSS Strat through a Micro Cube set to Recto with delay.
It's nice having a complete change of pace every once in a while, and the Micro Cube lets me play in my high rise apartment at 4AM without complaints.
For home it depends if I want to wake the neighborhood up to use my gigging rigs loud (kidding since I've done it before). Seriously I use either a Blues Jr, a Roland Micro Cube, Boogie Studio 22, Vox Pathfinder or a Princeton II. If I decide to use My Marshall Combo, Hot Rod Deluxe or Mesa Boogie MkIII I just keep the master volume down.